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No precise dose adjustment advisable when tofacitinib coadministered with potent CYP2C19 inhibitors; lower tofacitinib dose if coadministered with both equally reasonable CYP3A4 and powerful CYP2C19 inhibitors .As well as impairing Actual physical, cognitive, and psychosocial working, abnormal sleepiness compromises the security of people and the g

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